| 引用本文：王然然, 王斌.基于患者个体水平数据成本效果分析的主要问题和方法[J].中国卫生政策研究,2017,10(10):76-81 |
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| 基于患者个体水平数据成本效果分析的主要问题和方法 |
| 投稿时间：2017-06-29 修订日期：2017-09-07 PDF全文浏览 HTML全文浏览 |
| 王然然1,2, 王斌1,2 |
1. 中国中药协会中药药物经济学专业委员会 北京 100101;
2. 北京康派特医药科技开发有限公司 北京 100101 |
| 摘要:通过对国内外研究者的观点和解决方法进行整理总结，对基于患者水平数据的成本-效果分析的一般原则进行系统论述，并对分析中需要注意的问题进行探讨，包括分析数据集的选择，缺失/删失数据的处理，是否进行贴现的考虑，不确定性分析的使用，统计分析计划的制定，中间访视点的数据分析，协议驱动成本的处理等内容。 |
| 关键词:患者水平数据 成本-效果分析 一般分析原则 药物经济学 |
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| Key problems and methods of cost analysis based on individual cost of patients |
| WANG Ran-ran1,2, WANG Bin1,2 |
1. Pharmacoeconomics Profession-al Committee, Traditional Chinese Medicine of China, Beijing 100101, China;
2. Beijing Compete Medical Technology Development CO., Ltd, Beijing 100101, China |
| Abstract:By summarizing considerations and suggested solutions of domestic and foreign researchers, the general analysis principles of cost-effectiveness analysis based on patient level data are systematically discussed, as well as the problems that need to be paid attention in the analysis, including the analysis of data set, solution of missing/censored data, consideration of whether discount should be conducted, the use of uncertainty analysis, the preparation of statistical analysis plan, the analysis of intermediate follow-up point data, handling the protocol-driven costs, etc. The paper has provided reference and discussion points for the pharmaceutical economists or readers who may have interest. |
| Key words:Patient-level data Cost-effectiveness analysis Primary analysis principle Pharmacoeconomics |
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