| 引用本文：孙文俊, 赵子寅, 成哲玉, 李慧宁, 祝贺.药品集中采购政策对药品价格和使用影响的系统综述[J].中国卫生政策研究,2023,16(2):52-58 |
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| 药品集中采购政策对药品价格和使用影响的系统综述 |
| 投稿时间：2022-10-10 修订日期：2023-01-23 PDF全文浏览 HTML全文浏览 |
| 孙文俊1,2, 赵子寅1,2, 成哲玉1,2, 李慧宁1,2, 祝贺2 |
1. 北京大学公共卫生学院 北京 100191;
2. 北京大学中国卫生发展研究中心 北京 100191 |
| 摘要:目的：评价国家组织药品集中采购和使用政策对药品价格及用量的影响。方法：采用系统综述的方法检索中国知网、万方、维普、EMbase、PubMed和Web of Science六个数据库，提取和分析有关集采政策的实证研究结果。结果：本研究共纳入58篇文献，大多数文献发现集采政策实施后中选药品的限定日费用(DDC)明显下降，同类非中选药品的DDC也出现下降。同时，仿制药品的用药频度(DDDs)整体上大幅度增长，实现了对原研药部分国产替代。但是，集采政策的实施效果也存在一定的地区差异，部分药品出现了“量价脱钩”现象，需要进一步加强和完善。结论：基于对已有实证研究效果的总结评价，集采政策已经初步达到了其政策预期的效果，建议继续推进低价优质药品均等化，并加大政策宣传和药品质量与价格监管力度。 |
| 关键词:集采政策 用药频度 限定日费用 系统综述 |
| 基金项目:中央高校基本科研业务费专项资金资助项目(BMU2020YJ001) |
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| A systematic review on the impact of the volume-based procurement policy on prices and dosages of drugs |
| SUN Wen-jun1,2, ZHAO Zi-yin1,2, CHENG Zhe-yu1,2, LI Hui-ning1,2, ZHU He2 |
1. School of Public Health, Peking University, Beijing 100191, China;
2. China Center for Health Development Studies, Peking University, Beijing 100191, China |
| Abstract:Objective: To evaluate how the volume-based procurement policy influences prices and dosages of drugs. Methods: The data indicating empirical evaluation results of centralizing drug procurement from databases of CNKI, WanFang Data, VIP, EMbase, PubMed, and Web of Science were obtained and analyzed by using a systematic review approach. Results: Among 58 studies included,the majority showed a significant decrease the defined daily cost (DDC) of the selected drugs after the implementation of the volume-based procurement policy, together with a decrease in DDC of non-selected same kinds of drugs. Meanwhile, the defined daily doses (DDDs)of generic drugs increased in a big scale in general, which indicated the domestic replacements of some originally-developed drugs. However, there existed regional differences in terms of effects of the policy,and there were misconnections between quantities and prices of certain drugs that need to be regulated. Conclusion: According to previous empirical findings, the policy of central government purchasing drugs collectively realizes initial expectations. Further suggestions include promoting equalization of low-priced high-quality drugs, strengthening publicity of policies, and enforcing the supervision of drug quality and price. |
| Key words:Volume-based procurement policy Defined daily doses(DDDs) Defined daily cost(DDC) Systematic review |
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