我国基本药物制度实施效果研究进展评述

 
投稿时间: 2015-02-03  最后修改时间: 2015-03-14  摘要点击次数: 2649  全文下载次数: 1378
 
引用本文:方宇, 沈倩, 杨才君,等.我国基本药物制度实施效果研究进展评述[J].中国卫生政策研究,2015,8(4):12-17
方宇1,2, 沈倩1,2, 杨才君1,2, 常捷1,2, 武丽娜1,2, 杨世民1,2
1. 西安交通大学药学院 陕西西安 710061;
2. 西安交通大学药品安全与政策研究中心 陕西西安 710061
基金项目:国家自然科学基金面上项目(71473192);美国中华医学基金会OC公开竞标项目(14-196);西安交通大学青年教师跟踪支持项目(2015qngz05);中央高校基本科研业务费专项资金资助项目(sk2014041)
 
 摘要:目的: 系统评价国家基本药物制度实施效果的研究进展, 为进一步完善该制度提供参考。方法: 检索有关我国基本药物制度实施的国内外研究文献及国际组织报告, 时间跨度为2009年1月—2014年12月。结果:最终纳入文献1 292篇, 其中中文1 277篇, 英文12篇, 研究报告3篇。近年来我国基本药物制度研究文献众多, 但评价技术及指标不够完善, 样本代表性不足, 证据连续性欠缺, 利用医学大数据开展的循证评价研究刚刚起步, 国际合作研究较少。结论与建议:我国基本药物制度评价研究亟待加强。基本药物制度评价既要立足国情, 又要与国际的多维度评价框架相结合, 从可获得性、可支付性及合理用药等方面进行深入研究, 为基本药物制度的推进实施提供科学的证据支持。 
  关键词:国家基本药物制度  实施效果  可获得性  可支付性  合理用药
 
A review on implementation effects of National Essential Medicine System
FANG Yu1,2, SHEN Qian1,2, YANG Cai-jun1,2, CHANG Jie1,2, WU Li-na1,2, YANG Shi-min1,2
1. School of Pharmacy, Xi'an Jiaotong University, Xi'an Shannxi 710061, China;
2. The Center for Drug Safety and Policy Research, Xi'an Jiaotong University, Xi'an Shannxi 710061, China
 
 Abstract:Objective: To conduct a systematic review on the implementation effects of National Essential Medicine System (NEMS) since the new health care reform and provide some suggestions to further improve the NEMS. Methods: Databases and relevant international organization reports were searched to collect studies related to the implementation of NEMS in China. The database search occurred from January 2009 to December 2014. Results: A total of 1 292 studies were finally included, encompassing 1, 277 Chinese papers, 12 English papers, and 3 WHO/HAI reports. A lot of researches have been done on NEMS, but the techniques of NEMS evaluation are not perfect. The sample representativeness is poor, and the longitudinal follow-up studies of the microscopic view is insufficient.. Evidence-based evaluation research using big data has just started. Conclusions: The research on NEMS should be strengthened. The NEMS evaluation should not only be based on national conditions, but it should also be in combination with an international, multidimensional evaluation framework in terms of availability, affordability and rational drug use, so as to provide evidences to perfect the NEMS. 
 keywords:National Essential Medicine System  Implementation effect  Availability  Affordability  Rational drug use